Rob Stein

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Updated Oct. 14, 12:45 p.m. ET

If you got the Johnson & Johnson vaccine as your first COVID-19 shot, a booster dose of either the Moderna or Pfizer-BioNTech vaccine apparently could produce a stronger immune response than a second dose of J&J's vaccine. That's the finding of a highly anticipated study released Wednesday.

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For the first time, doctors are reporting that they have restored vision to people blinded by a rare genetic disorder using the revolutionary gene-editing technique known as CRISPR.

Carlene Knight's vision was so bad that she couldn't even maneuver around the call center where she works using her cane.

"I was bumping into the cubicles and really scaring people that were sitting at them," says Knight, who was born with a rare genetic eye disease.

But that's changed as a result of volunteering for a landmark medical experiment. Her vision has improved enough for her to make out doorways, navigate hallways, spot objects and even see colors.

"It's nice. I don't scare people and I don't have as many bruises on my body," Knight says, laughing.

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Americans may be able to breathe a tentative sigh of relief soon, according to researchers studying the trajectory of the pandemic.

The delta surge appears to be peaking nationally, and cases and deaths will likely decline steadily now through the spring without a significant winter surge, according to a new analysis shared with NPR by a consortium of researchers advising the Centers for Disease Control and Prevention.

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The pharmaceutical company Johnson & Johnson now says a booster shot to its COVID vaccine will improve immunity. Joining us now with details - NPR health correspondent Rob Stein. Good morning, Rob.

A head-to-head comparison of all three COVID-19 vaccines found Moderna is holding up better than Pfizer and the Johnson & Johnson vaccine provides the weakest protection.

But the researchers stressed that all three vaccines are still providing strong protection against people getting so sick that they end up in the hospital.

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