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President Obama has been able to fill one opening on a key appeals court, but three more remain. And GOP senators are signaling that they'll block those remaining nominations, saying the D.C. Circuit Court of Appeals doesn't really need that many judges.

The worldwide population of older people in need of care for Alzheimer's and related diseases will reach 277 million by the middle of the century, the authors say.

USIS, which processes thousands of background checks a year for the U.S., is being investigated for "systemic failure" to adequately vet employees and contractors. The company would not comment on the specifics of the Alexis investigation.

The Republican-controlled House is set to vote Friday on a stopgap spending bill to keep the government open for business through the middle of December. And the White House has already said if it makes it to the president's desk, he'll veto it. That's because the bill also would defund the Affordable Care Act.

A media investigation revealed this summer that scores of female inmates received prohibited sterilization procedures in California prisons between 1997 and 2010. State lawmakers are now demanding an audit into the legally questionable tubal ligations, to find out if coercion was involved.

Mass shootings provoke sorrow and outrage, but what actually changes? Not much in Congress regarding gun safety laws, but it's been a busy year for firearm and mental health legislation in states.

In what's thought to have been a gang-related incident, someone opened fire on a group of people in a park. The 3-year-old is in critical condition after a bullet struck his head.

Since emerging last year in the Middle East, a mysterious virus has infected at least 132 people and killed 58. But it's still unknown how people get infected. A genetic analysis now suggests that animals may have repeatedly infected people with the deadly virus.

Iran's new President Hassan Rouhani has launched a charm offensive ahead of his visit to the U.N. General Assembly next week, leading to speculation of a new course for relations with the U.S. But there are plenty of reasons for skepticism — Iran's history with the U.S. not the least of them.

A government shutdown could be looming if political leaders can't work out a federal budget deal. Host Michel Martin asks two former White House insiders, Ron Christie and Corey Ealons, what Congress and the president have to do to a shutdown.