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The U.S. Supreme Court hears arguments Monday in a case that looks at how municipal governments may regulate where and when signs are posted.

After three back-and-forth sets at the U.S. Open Tuesday night, Serena Williams advances to the semifinals. Steve Inskeep talks to Courtney Nguyen, a senior writer for WTA Insider.

The economy has improved dramatically in the Obama era. But problems still abound because of the soaring national debt, a deformed tax code, shrunken paychecks and a growing skills gap.

The South African city of Cape Town is running out of water. On Day Zero — April 16 — the taps will get turned off. As that day approaches, residents are thirsty for answers.

Three shots of the Pfizer-BioNTech COVID-19 vaccines for kids 6 months to under 5 prompted a strong immune response. Preliminary data suggests the vaccine is effective and safe.

Emergency management officials in Madison County said four were injured in addition to those killed when the tornado touched down southwest of Des Moines.

Take some time to enjoy pictures of the bigger and lesser- known moments from the winter games.

At least 91 people are dead after an earthquake struck the Indonesian island of Lombok Sunday, jolting nearby Bali. The quake comes a week after another earthquake hit both tourist destinations.

The National Transportation Safety Board strongly criticized Maryland officials for not determining the Francis Scott Key Bridge's risk of collapse. The bridge collapsed after a cargo ship struck it.

A panel of experts voted 8-6 in favor of Food and Drug Administration approval of the first gene therapy for Duchenne muscular dystrophy, a fatal genetic disease.