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President Biden has faced a number of major setbacks to various parts of his agenda — from COVID-19 to the economy to voting rights and the rest of his agenda in Congress.

Three states go to the polls Tuesday, starting what will be an eight-week stretch of primaries in the U.S. For a look at the intra-party political landscape, NPR's Charlie Mahtesian has this overview.

NPR's Audie Cornish speaks with Rep. Brian Higgins, D-N.Y., who has spoken publicly about his opinion that it's time for new Democratic leadership as more than 40 nominees for House seats have said they would not vote for minority leader Nancy Pelosi as Speaker of the House.

Ailsa Chang talks to Democratic Sen. Ben Cardin, of the Senate Foreign Relations Committee, about how the U.S. might respond to the threats posed by North Korea's nuclear weapon capabilities.

Photographer Andria Hautamaki is used to limited connectivity, living on an off-grid ranch in Chilean Patagonia. Now, her access to the Internet and other humans is further reduced.

Photographer Minik Bidstrup, who is of Greenlandic Inuit background, seeks to confront the country's long colonial history from an indigenous perspective: "We are still here in the land we call home."

President Biden's pick for the next director of the CDC is Dr. Mandy Cohen, an internal medicine physician with experience in state and federal government.

Stephanie Williams discovered comics young, drawn early to X-Men, which she saw as an allegory for the persecution of black Americans. An adult now, she co-hosts a podcast about black superheroines.

The new Netflix comedy special focuses almost entirely on stories about a guy who acts like a foolish, self-destructive doofus: John Mulaney as he entered rehab.

A "declaration of principles" that sets the foundation for the future of America's involvement in Iraq is raising questions on Capitol Hill about how long the U.S. commitment there will last.